Abstract
Enol acetates of a-keto esters with E configuration were prepared as potential prodrugs for human neutrophil elastase (HNE) inhibitors.
MeSH terms
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Acetates / chemistry*
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Esters
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Humans
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Leukocyte Elastase / antagonists & inhibitors*
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Prodrugs / chemical synthesis*
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Prodrugs / pharmacology
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Protease Inhibitors / chemical synthesis*
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Protease Inhibitors / pharmacology
Substances
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Acetates
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Esters
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Prodrugs
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Protease Inhibitors
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Leukocyte Elastase